Chapter 1 detailed the synthesis method of hydroxamate peptides derivatives of pentapeptide Ac-PHSXX\'-N-NH2 by solid phase hydroxamate peptide synthesis method. The glutamic acid/aspartic acid side chain was modified to hydroxamic acid by on resin...
Drug delivery systems; Curcumin--Therapeutic use--Administration
Curcumin, a plant derived compound has shown significant potency against various chronic diseases like cancer in cell culture and animal studies. However, the introduction of this compound into clinical setting is limited by its poor oral...
Aim. To compare two techniques of ridge preservation using a mineralized cancellous particulate allograft to a mineralized cortical particulate allograft plus an acelluar dermal matrix barrier membrane using clinical and histologic data to assess...
Aim. Differences in the healing of demineralized and mineralized allografts have been reported but their significance has not been evaluated in ridge preservation studies. The primary aims of this study were to compare ridge preservation using a...
Aim. The efficacy of ridge preservation procedures using grafting materials and barrier membranes has been well established in the literature. However, the loss of horizontal width even with the utilization of intrasocket only guided bone...
The vaccinia virus complement control protein (VCP) is involved in the modulation of the host inflammatory response during vaccinia virus infection. It possesses the ability to inhibit both classical and alternative pathways of complement...
Liver--Diseases--Genetic aspects; Liver--Effect of arsenic on; Arsenic--Toxicology
Arsenic exposure in drinking-water is a significant worldwide health problem. It causes adverse human health effects, such as cancer, increases the risks for others such as cardiovascular disease, and accelerates atherosclerosis. In this study, we...
Orthodontics; Dental care--Kentucky; Health services accessibility--Kentucky
Background: Malocclusion can affect an individual's quality of life. Unfortunately, access to orthodontic treatment is limited for many children. Access is improved when orthodontists select practice locations where their services are most needed....
Feminism in art; Art, Mexican; Women in art; Art and society--Mexico
This dissertation outlines a theoretical model for contextualizing contemporary
women's art practice in Mexico within the profound socioeconomic and political events
that have taken place since 1968, characterized by the steady breakdown and...
Swarm Intelligence (SI) techniques were inspired by bee swarms, ant colonies, and most
recently, bird flocks. Flock-based Swarm Intelligence (FSI) has several unique features, namely
decentralized control, collaborative learning, high exploration...
Pattern recognition systems; Land mines--Detection; Pattern perception--Data processing; Data mining
Traditional machine learning and pattern recognition systems use a feature descriptor to describe the sensor data and a particular classifier (also called "expert" or "learner") to determine the true class of a given pattern....
Pattern perception--Data processing; Pattern recognition systems; Land mines--Detection; Data mining
For complex detection and classification problems, involving data with large intra-class variations and noisy inputs, no single source of information can provide a satisfactory solution. As a result, combination of multiple classifiers is playing...
Arsenic--Physiological effect; Cardiovascular system--Diseases; Liver--Effect of arsenic on; Arsenic--Toxicology
Chronic arsenic exposure is associated with increased cardiovascular disease (CVD). Prenatal arsenic exposure at 49 ppm arsenic accelerates atherosclerosis underlying CVD in ApoE-/- mice, but the mechanism is unknown. This dissertation examines the...
Several technical and economic obstacles currently hamper the industrial development of ethanol from biomass. One of the key bottlenecks is the slow kinetics of the enzymatic hydrolysis of cellulose, and the subsequent rate reduction as the...
Java (Computer program language); Application software--Development
The purpose of this thesis is to design, implement, and evaluate a software package that is mutli-platform and will provide software integrity management (SIM). The software package is implemented in Java and will perform two hashing algorithms,...
The oxidation of metallothiolates is complicated by "non-innocence" or potential
redox activity of sulfur to yield thiyl (RS•) radicals. In some instances, the one-electron
oxidation of metal thiolates yields a product with the unpaired...
Rhetoric--Political aspects--United States; African American women--Economic conditions; African American women--Social conditions; Public welfare--United States--History--20th century
This dissertation is a rhetorical analysis of the political discourse surrounding the role of poor African American women within the American social and political economy beginning in 1965 with Lyndon Johnson's War on Poverty initiatives and...
Historic sites; Buildings; Monuments & memorials; Abraham Lincoln Birthplace National Historic Site (Ky.); Lincoln, Abraham, 1809-1865
Memorial Building at Abraham Lincoln Birthplace National Historic Site near Hodgenville, Kentucky. The memorial is a stately neoclassical building reached by a series of stairs. It houses a replica of the log cabin in which President Abraham...
Buildings; University of Louisville--Buildings; Barracks; Dormitories; University of Louisville. School of Business; Southern Police Institute
Menges Hall, a former barracks building used for various purposes by the University of Louisville. The side of the building is fully visible; part of another barracks building is visible behind it. A Gulf Oil sign rises above it in the rear. The...
Background: Emerging circulatory support devices that operate in counterpulsation to the native heart require synchronized timing of device ejection and filling on a beat-to-beat basis with the native heart using a patient's ECG. Surface leads are...
