Hyaluronan (HA) is a major structural component of the ocular vitreous humor
(VH) and lipids are essential building blocks of cell membranes. However, little is known
about their possible interactions. The VH is known to undergo liquefaction...
Modular hip implants are currently being used in total hip arthroplasty revision procedures because it is common to have little or no bone left in the proximal region of the femur and it is difficult to accurately size implants based off of...
Sex offenders--Psychology; Sex offenders--Research
Based primarily on theory, it is suspected that violent and non-violent sex-offenders can be differentiated by their psychopathic profile, as measured by the Psychopathy Checklist-Revised (PCL-R; Hare, 1991). There is some concern that current...
Here, I address the function of the carboxy-terminal hydrophobic helix of the pro-apoptotic protein Bax. There has been considerable controversy as to whether this sequence is required for the targeting and insertion of Bax into the mitochondrial...
Writing centers; English language--Rhetoric--Study and teaching (Higher); Tutors and tutoring
Using Gloria Anzuldula's text Borderlands/La Frontera: The New Mestiza and Bruce Homer and Min-Zhan Lu's 2000 article, "Expectations, Interpretations and Contributions of Basic Writing" as conceptual framework, I conducted my dissertation...
The use of franchise advisory boards, typically composed of franchisees and
franchisor representatives, is common practice in domestic and international franchise
systems. Because effective board collaboration requires teamwork, understanding...
The purpose of this research is to understand how the process parameters surrounding the Direct Metal Deposition (DMD) process affect the properties of the deposition. The powder used in this research is pre-alloyed titanium powder (Ti-6Al-4V),...
The goal of this study was to investigate the relationships between school climate, school culture, teacher efficacy, collective efficacy, teacher job satisfaction and intent to turnover in the context of year-round education (YRE) calendars. The...
Intimate partner violence--Psychological aspects; Victims of family violence--Rehabilitation; Victims of violent crimes--Mental health; Creative writing--Therapeutic use; Post-traumatic stress disorder--Treatment
Described as important long-term consequences of trauma exposure, disruptions in emotional processes are regarded as central features of posttraumatic stress disorder (PTSD); however, the nature of these posttraumatic emotional disruptions remains...
Mucin 1 (MUC1) is a plasma membrane-bound glycoprotein that plays a protective role in corneal epithelial cells. Two full-length splice variants of MUCl: MUCl/B and MUCl/A, that differ by the inclusion of 27 bp from intron 1 and a SNP in MUCl/A,...
A hyper basis function network (HyperBF) is a generalized radial basis function network (RBF) where the activation function is a radial function of a weighted distance. The local weighting of the distance accounts for the variation in local scaling...
Vicinal dithioethers and alkenyl thioethers were synthesized under environmentally
friendly conditions using alkyne and thiol in water. Alkynes were also used to develop a
multibond-fonning reaction that fonned cyclic ketones or ketoesters through...
High-throughput sequencing has provided a myriad of genetic data for thousands of organisms. Computational analysis of one data type, expressed sequence tags (ESTs) yields insight into gene expression, alternative splicing, tissue specificity gene...
Ischemic heart disease is the leading cause of mortality and morbidity in Western societies. Thus, understanding the molecular mechanisms to reduce myocardial ischemia and limit infarction size are of great importance. Ample evidence has shown that...
Estimating and analysis of deformation, either rigid or non-rigid, is an active area of research in various medical imaging and computer vision applications. Its importance stems from the inherent inter- and intra-variability in biological and...
Skeletal muscle is the most abundant tissue in our body that provides a structural framework and regulates important biological processes. It is also a primary reservoir of protein. Skeletal muscle maintains its structural and functional integrity...
The role of the active site tyrosine residue in the Co-C5' bond activation in the
context of adenosylcobalamin-dependent mutases has been computationally
investigated. The density functional, complete active space self-consistent field
and quantum...
Sleep disorders in children; Children--Sleep; Blind children
Research has confirmed that individuals with blindness have an increased risk of
developing sleep problems; this is especially problematic for families with young
children who are blind. Not only does the lack of sleep impact the growth...
This dissertation is a participatory action research project with adults with mental retardation who reside in Louisville, Kentucky. It explores some of the history and ideologies that frequently have hindered persons with mental retardation from...
