Computer sound processing; Computer-assisted instruction; Educational games
Educational games have steadily entered classrooms as a means of challenging advanced students and tutoring those lacking comprehension. However, without adequate educational benefits, instructors are struggling to continually justify the marginal...
Leather-bound guest book dating from 1948 to 2011, featuring signatures of attendees of Louisville Orchestra premieres; Grawemeyer Composition winners; and official guests of the School of Music.
Web search engines; Automatic abstracting; Graph theory--Data processing
After a user types in a search query on a major search engine, they are presented with a number of search results. Each search result is made up of a title, brief text summary and a URL. It is then the user's job to select documents for...
Liver--Diseases--Genetic aspects; Liver--Effect of arsenic on; Arsenic--Toxicology
Arsenic exposure in drinking-water is a significant worldwide health problem. It causes adverse human health effects, such as cancer, increases the risks for others such as cardiovascular disease, and accelerates atherosclerosis. In this study, we...
Background: Helicobacter pylori (Hp) establishes life-long gastric infection in billions of humans, and is often responsible for diseases such as peptic ulcer and gastric cancer. Cumulative actions of genetic drift and natural selection over...
c-Myc dysregulation is one of the most common abnormalities found in human cancer. MicroRNAs (miRNAs) are functionally intertwined with the c-Myc network as multiple miRNAs are regulated by c-Myc, while others directly suppress c-Myc expression. In...
Chlamydia trachomatis is an obligate intracellular pathogen that utilizes a type III secretion system to enter mammalian cells and establish an intracellular niche. TARP, the translocated actin recruitment protein, is a chlamydial invasion protein...
Current high-throughput gene expression experiments have a straightforward design of examining
the gene expression of one group or condition relative to that of another. The data is typically
analyzed as if they represent strictly intracellular...
Dimorphism is a highly conserved process in fungi in which a transition between a unicellular, yeast-like growth form and either a unicellular or multicellular, filamentous growth form occurs in response to several different environmental cues. The...
Due to the complex nature of interactions at the genomic level as well as the large number of proteins present in an organism, understanding the functions of various genes that are expressed is essential. Creating an analysis pipeline for Expressed...
Exocytosis of intracellular granules is critical for conversion of inactive, circulating neutrophils to fully activated cells. The p38 MAPK pathway plays a central role in neutrophil exocytosis, although its mechanism of action is unknown. We used...
Faded portrait of unidentified man with beard and mustache, wearing tuxedo with black bow tie. Annotated on print, lower left: 20 [cents]. Title supplied by cataloger.
From a computerized image analysis prospective, early diagnosis of lung cancer involves detection of doubtful nodules and classification into different pathologies. The detection stage involves a detection approach, usually by template matching,...
High-throughput sequencing has provided a myriad of genetic data for thousands of organisms. Computational analysis of one data type, expressed sequence tags (ESTs) yields insight into gene expression, alternative splicing, tissue specificity gene...
Computer vision; Pattern recognition systems; Human face recognition (Computer science)
Humans have the uncanny ability to perceive the world in three dimensions (3D), otherwise known as depth perception. The amazing thing about this ability to determine distances is that it depends only on a simple two-dimensional (2D) image in the...
In the age of high-throughput molecular biology techniques, scientists have incorporated the methodology of in-situ hybridization to map spatial patterns of gene expression. In order to compare expression patterns within a common tissue structure,...
Lung cancer is the deadliest type of known cancer in the United States, claiming hundreds of thousands of lives each year. However, despite the high mortality rate, the 5-year survival rate after resection of Stage 1A non–small cell lung cancer...
Three-dimensional imaging in medicine; Lungs--Cancer--Diagnosis
Many lung diseases or injuries can cause biomechanical or material property changes that can alter
lung function. While the mechanical changes associated with the change of the material properties
originate at a regional level, they remain largely...
Map of Louisville, Kentucky, with Jeffersonville and New Albany, Indiana visible north of the Ohio River. Includes electronic railways and railroads (further annotated in ink), as well as locations of utilities, parks, cemeteries, institutions, and...
Marginal inference for waiting times in multi-stage time-to-event models is complicated by right censoring of observations as well as the prior history of events in the model. In general, complications arise due to the evolution of the censoring...
