Previous studies on the mechanistic induction of anti-tumor responses by IL-12 cytokine therapy have focused on the adaptive immune response, specifically the activation NK cells and T cells as the primary targets of IL-12 treatment. In contrast,...
Algebra--Study and teaching; Academic achievement; Teachers--Attitudes
The purpose of this study was to investigate various secondary to postsecondary mathematics transition issues for students. Making successful transitions from high school to postsecondary study has become necessary if our nation's young people are...
Monoclonal antibodies directed toward tumor associated antigens are FDA approved anticancer reagents used commonly in the clinic. Administered antibodies initiate tumor cell death through several mechanisms. Improving immune mediated mechanisms,...
Human being can easily acquire information by showing the object than reading the description of it. Our brain stores images that the eyes are seeing and by the brain mapping, people can analyze information by imagination in the brain. This is the...
Background - Cranial cruciate ligament (CrCL) rupture in the canine stifle is a leading
cause of orthopedic lameness in the dog. Several corrective surgical procedures have
been developed to return dogs to pre-injury function following CrCL...
In blood coagulation, the serine protease thrombin is a multifaceted enzyme that interacts with multiple proteins. Thrombin utilizes two anion binding exosites (ABE-I and II) to supplement binding to fibrinogen and to the platelet receptor GpIbα,...
Epithelial Ovarian cancer (EOC) is the leading cause of gynecological cancer death in the USA. Recurrence rates are high after front-line platinum chemotherapy and most patients eventually die from platinum-resistant disease. P53 plays an important...
An investigation was made into the relative costs of excavation retention by two systems: conventional soldier pile-wale-tieback support, and support by soil nailing. The investigation included design of excavation supports by the two...
Drug resistance in microorganisms; Salmonella typhimurium
Salmonella enterica serovar Typhimurium is an enteric pathogen capable of infecting
a wide range of hosts. The manner in which this pathogen is able to interact with its
host is difficult to define, as is the case with most microbes. Through the...
A combination of three techniques – high resolution micro computed tomography (micro CT) scanning, Archimedes-based volume fraction measurement and serial sectioning or milling – were used to determine the volume fraction, trabecular thickness,...
Knee--Mechanical properties; Knee--Pathophysiology; Gait in humans; Osteoarthritis
Osteoarthritis (OA) of the knee is associated with decline in functional capacity and ultimately leads to Total Knee Arthroplasty (TKA) in many of these patients. Exercise regimens prior to surgery may potentially enhance pre and post TKA...
Previous research on organizational mergers has found that such a business activity bears an effect upon the structural and cultural foundations of organizations. Whether combining intellectual resources or capital, mergers combine workforces that...
Microelectromechanical systems; Biotelemetry; Strains and stresses--Measurement
Lumbar arthrodesis or spinal fusion is usually performed to relieve back pain and regain functionality from ruptured discs, disc degenerative disease, trauma and scoliosis. Metal rods are often fixed to the spine with screws or hooks, while fusion...
This quantitative dissertation examines outcomes of a required service-learning program at a faith-based institution. Two hundred and ten students completed a pre/post survey administered to a sophomore level class about background, educational...
Aluminum fiber metal laminates (AFMLs) are a promising new type of fiber metal laminate that consists of aluminum foils interleaved with layers of a graphite fiber-polymer matrix composite (PMC) material. AFMLs combine the attractive features of...
Chlamydia trachomatis is an obligate intracellular pathogen that utilizes a type III secretion system to enter mammalian cells and establish an intracellular niche. TARP, the translocated actin recruitment protein, is a chlamydial invasion protein...
English literature--Early modern, 1500-1700; Geographical discoveries in literature
It is the purpose of this thesis to show what influence the sixteenth century voyagers had on the Elizabethan writers. For expediency, we have divided these voyages into two classes: namely, the early, from Columbus, 1492, to Vasca de Gama, 1498;...
Louisville (Ky.)--Economic conditions--19th century; Louisville (Ky.)--Commerce--History; Ohio River Valley--Commerce--History
The dominant theme in the study of any phase of Ohio River history is found in the great extent of the river system and the vast area of the drainage basin of the Mississippi to which this stream forms so important a part. The basin of the...
Welfare recipients--United States; College students--United States
Using Schlossberg's transition theory as the conceptual framework, this case study explored and identified the coping strategies used by seven welfare recipients attending postsecondary institutions. Three participants were enrolled in the local...
Gay rights; Gays--Employment; Bullying in the workplace
Employee retention continues to be a major drain on the resources of organizations, especially in terms of personnel, productivity, and financial resources. One of the primary motivators of employee turnovers established by research is the issue of...
