4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are highly reactive á,â-unsaturated aldehydes. 4-HNE and acrolein are generated in vivo as products of lipid peroxidation. These aldehydes are implicated in the onset of several diseases...
Sculpture; Mixed media; Women; Women's rights; Feminism; Feminists; Sexism; Stereotyping; Discrimination; Sex; Genitals; Body parts; Human body; Biology; History; Arts & crafts; Dinner parties; Celebrations; Parties; Guests; Dining tables;...
"Each of the ceramic plates adorning the table in this installation was individualized. In this photograph, the Georgia O'Keeffe plate on the right owed something of its original design to her Black Iris paintings of the mid-1920s. The plate...
Performance art; Performances; Painting; Body painting; Locomotion; Human locomotion; Artists; Men; Dandies; Women; Nudes; Audiences; Spectators; Orchestras; Music ensembles; Musicians; Sitting; Musical instruments; Clothing & dress; Suits...
"This performance exemplifies Klein's participation in the masculinist tradition of the dandy. The self-contained male, renouncing biological productivity (symbolized by the 'fecundity' of the paint-covered women launching themselves at...
A common research interest in medical, biological, and engineering research is determining whether certain independent variables are correlated with the survival or failure times. Standard statistical techniques cannot usually be applied for...
Among gynecological malignancies, carcinoma of the cervix is the leading cancer type worldwide. Conversely, vaginal tumors account for an incidence of approximately 1-2% of lower genital tract malignancies. Interestingly, the major shared risk...
Background: Helicobacter pylori (Hp) establishes life-long gastric infection in billions of humans, and is often responsible for diseases such as peptic ulcer and gastric cancer. Cumulative actions of genetic drift and natural selection over...
Cancer patients show circadian disruption that increases as disease progresses. Disrupted endocrine and activity rhythms predict early metastatic cancer mortality. Effects of psychological versus biological factors on rhythms are unknown, as are...
Current high-throughput gene expression experiments have a straightforward design of examining
the gene expression of one group or condition relative to that of another. The data is typically
analyzed as if they represent strictly intracellular...
DNA microarrays--Statistical methods; Gene expression--Statistical methods
Data derived from gene expression microarrays are frequently used to identify candidate genes which can characterize and distinguish between two biological phenotypes. A key step in this process is the selection of an appropriate test statistic to...
Dehydroepiandrosterone (DHEA) is a C-19 adrenal steroid and the most abundant circulating hormone in humans. Since circulating levels decline in late adulthood, treatment of humans with DHEA has been suggested to have beneficial health effects....
Estimating and analysis of deformation, either rigid or non-rigid, is an active area of research in various medical imaging and computer vision applications. Its importance stems from the inherent inter- and intra-variability in biological and...
Buildings; Research facilities; University of Louisville--Buildings;
Exterior shot of the Center for Predictive Medicine; includes a corner of the building, an entrance and tables on a patio. Location: Shelby Campus: 950 North Hurstbourne Lane. Current uses: A level-3 biosafety lab (meaning that researchers are...
Few previous studies have compared microbial communities in subterranean and surface environments. Chemical analyses used to characterize the surface and cave microbial environments indicated limited exchange between surface and subsurface waters....
Schiller, Friedrich, 1759-1805. Über die ästhetische Erziehung des Menschen in einer Reihe von Briefen; Schiller, Friedrich, 1759-1805--Philosophy; Play (Philosophy)
Friedrich Schiller's psychological theory of play, his hypothesis about human nature, is embedded in the Aesthetic Letters . Its trans-historical value owes much to the committed interest in life in the late Enlightenment, and the theory itself is...
G-quadruplexes are thought to have biological importance, with studies based on small molecule interactions and quadruplex-interactive antibodies demonstrating their potential for formation in vivo. One potential biological function of quadruplex...
Griffithsin (GRFT) is a carbohydrate binding protein derived from the red alga Griffithisia sp. that has been shown to effectively interfere with the cellular attachment and infectivity of a number of viruses, including HIV-1. However, it is...
Guanine-rich oligonucleotides (GROs) are being developed as a novel anticancer agents. GROs exhibit potent antiproliferative properties against several malignant cell lines and in established in vivo tumor models. In a recent Phase I clinical trial...
Inflammatory bowel disease (IBD) is a chronic autoimmune disorder that is subdivided into Crohn's disease (CD), ulcerative colitis (UC), and indeterminate colitis (IC). Epidemiological studies have proven that genetic variation increases...
Many conflicting reports have been given in the literature concerning the effect of various factors on the rate of reversal of figure and ground in reversible perspective.
Flugel (7, 8) suggested that changes in eye movement increased the number of...
MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level by repressing translation or stimulating mRNA degradation. In this study, I tested the hypothesis that miRNAs are differentially expressed in antiestrogen-sensitive MCF-7...
