N-acetyltransferase 1 (NAT1) is a phase II metabolic enzyme responsible for the biotransformation of aromatic and heterocyclic amine carcinogens such as 4-aminobiphenyl (ASP). NAT1 catalyzes N-acetylation of arylamines as well as the 0-acetylation...
Arrhythmia; Heart--Diseases; Heart beat; Heart conduction system
Introduction: Hyperhomocysteinemia (HHcy) is a pathological condition characterized by excessive levels of plasma homocysteine (Hcy). Patients with HHcy are reported to be at risk for arrhythmias like atrial fibrillation and sudden cardiac death...
Externalizing behavior problems in very young children are associated with an array of negative and costly long-term outcomes. Pediatric primary care is a promising venue for implementing screening practices to improve early identification of this...
MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level by repressing translation or stimulating mRNA degradation. In this study, I tested the hypothesis that miRNAs are differentially expressed in antiestrogen-sensitive MCF-7...
Data from the Health and Retirement Study (HRS) were used to examine factors that influence emotional distress in older adults with cancer, arid to learn whether these distress trajectories are different from older adults without cancer. The model...
While investigating estrogen response element (ERE) binding properties of Erα in de-identified human breast cancer extracts, additional proteins were observed that recognized ERE sequences (ERE-BP). In order to unravel the apparent role of these...
Few previous studies have compared microbial communities in subterranean and surface environments. Chemical analyses used to characterize the surface and cave microbial environments indicated limited exchange between surface and subsurface waters....
Chlamydia trachomatis is an obligate intracellular pathogen that utilizes a type III secretion system to enter mammalian cells and establish an intracellular niche. TARP, the translocated actin recruitment protein, is a chlamydial invasion protein...
Phase II clinical trial are generally single arm trial where a homogeneity assumption is placed on the response. In practice, this assumption may be violated resulting in a heterogeneous response. This heterogeneous or overdispersed response can be...
This thesis proposes a network based intrusion detection approach using anomaly detection and achieving low configuration and maintenance costs. A honeypots is an emerging security tool that has several beneficial characteristics, one of which is...
Rootkits are stealthy, malicious software that allow an attacker to gain and maintain control of a system, attack other systems, destroy evidence, and decrease the chance of detection. Existing detection methods typically rely on a priori knowledge...
Traffic sign (TS) detection and tracking is one of the main tasks of an autonomous vehicle which is addressed in the field of computer vision. An autonomous vehicle must have vision based recognition of the road to follow the rules like every other...
Corpus callosum; Diagnostic imaging; Autism--Diagnosis
Early detection of human disease in today’s society can have an enormous impact
on the severity of the disease that is manifested. Disease such as Autism and Dyslexia,
which have no current cure or proven mechanism as to how they develop, can...
Elementary school principals--Attitudes; Educational leadership; Sex role in the work environment; Sex role--Psychological aspects
Research has shown that various leadership styles have different impacts on leader outcomes such as satisfaction, extra effort, and effectiveness. Specifically, researchers have found that transformational leadership positively impacts follower...
Human adult olfactory epithelium contains neural progenitors (hONPs) which replace damaged cellular components throughout life. Methods to isolate and expand the hONPs have been developed in our laboratory. In response to morphogens, the hONPs...
Exocytosis of intracellular granules is critical for conversion of inactive, circulating neutrophils to fully activated cells. The p38 MAPK pathway plays a central role in neutrophil exocytosis, although its mechanism of action is unknown. We used...
Traditionally, fingerprint image acquisition was based on contact. However
the conventional touch-based fingerprint acquisition introduces some problems
such as distortions and deformations to the fingerprint image. The most recent
technology for...
From Delphi. "Some scholars, however, on the basis of inscriptions detected on the base and (by one scholar) on the heroes' thighs, prefer to identify them as the Dioskouroi (Castor and Pollux)."; they are "associated with a regional...
Background: Helicobacter pylori (Hp) establishes life-long gastric infection in billions of humans, and is often responsible for diseases such as peptic ulcer and gastric cancer. Cumulative actions of genetic drift and natural selection over...
Computer-aided minimally invasive surgery (MIS) has progressed significantly in the last decade and it has great potential in surgical planning and operations. To limit the damage to nearby healthy tissue, accurate modeling is required of the...
