Accelerated life testing; Reliability (Engineering); Service life (Engineering)
This dissertation is focused on finding lower confidence limits for the reliability of systems consisting of Wei bull components when the reliability demonstration testing (RDT) is conducted with zero failures. The usual methods for the parameter...
The inherited bone marrow failure syndromes (IBMFS) encompass a heterogeneous collection of rare disorders characterized by hematological abnormalities, generalized growth delays, and an increased incidence of malignant transformation. These...
Cancer accounts for nearly one-quarter of deaths in the United States, exceeded only by heart diseases. Despite the development of various strategies to treat cancer, it remains one of the most deadly diseases worldwide due to the limited effects...
Children's literature in mathematics education; Mathematics--Study and teaching (Elementary); Problem youth--Education (Elementary); Mathematics--Remedial teaching
Nationally, there are increasing numbers of students who are at-risk for academic and/or social failure (U.S. Department of Education, 2009). In an attempt to address this trend, the 2004 reauthorization of the Individuals with Disabilities...
Computational grids are some of the largest computer systems in existence today. Unfortunately they are also, in many cases, the least reliable. This research examines the use of redundancy with permutation as a method of improving reliability in...
The use of fiber reinforced polymer materials (composite FRP materials) to
strengthen existing concrete structures continues to expand as our current infrastructure
ages. However, one of the concerns when using FRP systems in this manner is...
Electroactive polymers (EAPs), including conducting polymers (CPs) such as polyaniline (PAn), and hydrogels are exciting areas of research in disciplines such as biomedical engineering, with the goal of creating low-cost, lightweight, non-toxic...
Conducting polymers; Polymers in medicine; Myocardium
Hydrophilic and conductive characteristics in polymers are mutually exclusive of each other. Hydrophilic polymer properties allow absorption of water up to several magnitudes above their dry weight. However, due to their molecular structure, they...
Purpose: The initial and long term bond failure rates of two orthodontic indirect bonding methods were compared. Materials and Methods: A review of 191 bondings provided a data base of bond failures for two indirect bonding methods. One method used...
Diabetic cardiomyopathy (DCM) is a common complication leading to accelerated cardiovascular failure in diabetic patients. Even though the exact mechanism(s) behind this disease still remain unclear, research from several laboratories including our...
In the electronic and microfabrication industry, die separation is one of the most critical steps in producing an undamaged, stand-alone micro-scale device. For silicon based devices, it is the predominant step governing resistance to die failure...
Modular hip implants are currently being used in total hip arthroplasty revision procedures because it is common to have little or no bone left in the proximal region of the femur and it is difficult to accurately size implants based off of...
Former Soviet republics--Politics and government; Youth movements--Former Soviet republics; Georgia (Republic)--Politics and government--1991-; Kyrgyzstan--Politics and government--1991-; Ukraine--Politics and government--1991-
In 1991, as democratic ideals spread through the former Soviet sphere, newly independent nations and satellite countries began engaging in the truly challenging, albeit hopeful task of dual state- and democracy-building endeavors. After twenty...
Health--Information resources; Health--Information services; Information networks
Background: Failure to achieve their goals of over 200 U.S. Health Information Exchange Networks (HIENs) which formed or operated in the U.S. from 2004 to 2010, lost time, capital and opportunity at individual, organizational and societal levels,...
Heart--Hypertrophy; Heart--Physiology; Sugar in the body; Metabolism; Diabetes--Research
Heart failure is recognized as a major cause of death among diabetics. In type I and II diabetes, glucose uptake, glycolysis and pyruvate oxidation are impaired, and fatty acid utilization increases. These alterations in metabolism contribute...
Heart--Hypertrophy; Hydrogen sulfide--Therapeutic use
Background: Although matrix metalloproteinase (MMPs) and tissue inhibitor of metalloproteinase (TIMPs) play a vital role in tumor angiogenesis and TIMP-3 causes apoptosis, their role in cardiac angiogenesis is unknown. Interestingly, a disruption...
Background The anthracycline doxorubicin (DOX) is widely used as an effective antineoplastic drug. Cardiotoxicity leading to congestive heart failure is the primary factor limiting the clinical use of DOX. However, although a variety of approaches...
Heart failure is the most frequent cause of mortality in western countries. Currently, there is no cure treatment for heart failure and the long term survival rate following heart failure is poor, with one third of patients dying within a year of...
