In blood coagulation, the serine protease thrombin is a multifaceted enzyme that interacts with multiple proteins. Thrombin utilizes two anion binding exosites (ABE-I and II) to supplement binding to fibrinogen and to the platelet receptor GpIbα,...
Metastasis is a complex process requiring directed migration of metastatic cells to favorable microenvironments. Increased CXCR4 expression has been implicated in more invasive, aggressive and metastatic tumor phenotypes and poor patient survival...
African Americans; African American physicians; Physicians; Hospitals; Red Cross Hospital (Louisville, Ky.); Race relations; Integration
Oral history interview with Louisville physician Jesse Bell conducted on July 28, 1979 by Olivia Frederick. Dr. Bell discusses his early life and education, including his training at Alcorn College, Morehouse College, and Meharry Medical College....
The goal of this longitudinal, multilevel study was to develop a better understanding of poor renter households' mobility patterns by identifying the relative importance of individual and contextual variables. Variability in neighborhood poverty...
The vast knowledge of nucleic acids is evolving and it is now known that DNA can adopt highly complex, heterogeneous structures. Among the most intriguing are the G-quadruplex structures, which are thought to play a pivotal role in cancer...
This dissertation takes Chinese advertisements as the research subjects to see in what way a quantifiable large number of advertisements with its metaphorical nature and instrumental mission can reflect social cultural change, in specifics,...
Pattern recognition systems; Land mines--Detection; Pattern perception--Data processing; Data mining
Traditional machine learning and pattern recognition systems use a feature descriptor to describe the sensor data and a particular classifier (also called "expert" or "learner") to determine the true class of a given pattern....