In blood coagulation, the serine protease thrombin is a multifaceted enzyme that interacts with multiple proteins. Thrombin utilizes two anion binding exosites (ABE-I and II) to supplement binding to fibrinogen and to the platelet receptor GpIbα,...
The current study examined how Disclosure, Stereotype Disconfirming Information, and Stereotype Disconfirming Information and Disclosure Combined) influences an individual's stigma (stereotype endorsement, emotional reactions, and discrimination)...
This work examines our perception of distance within "action space" (about 2m ~ 30m), an ability that is important for various actions. Two general problems are addressed: what information can be used to judge distance accurately and how...
The role of the active site tyrosine residue in the Co-C5' bond activation in the
context of adenosylcobalamin-dependent mutases has been computationally
investigated. The density functional, complete active space self-consistent field
and quantum...
Unrepaired DNA damage poses a serious threat to the genetic stability of a replicating cell. One mechanism of tolerating this damage is translesion DNA synthesis (TLS), in which an accessory polymerase synthesizes DNA directly across from a damaged...
College students--Attitudes; College dropouts; Dropout behavior, Prediction of; Academic achievement; Prediction of scholastic success
This study explored the relationship between engagement in educationally purposeful activities during the first year of college and academic achievement, persistence, and graduation. The study focused on the impacts of engagement on student...
In the course of their life cycle, mosquitoes undergo an ontogenetic niche shift; immature larval development occurs within an aquatic habitat from which adult mosquitoes subsequently disperse into the terrestrial environment. While adult female...
Farmers' markets--Kentucky--Louisville; African Americans--Nutrition; African American consumers--Kentucky--Louisville; Health promotion--Kentucky--Louisville--Citizen participation; Food--Social aspects
The purpose of this study is to obtain a better understanding of the interactions and the
social environment of the local farmers' markets, Fresh Stops, and Healthy in a Hurry
Corner Stores in West Louisville and East Downtown. This study will...
Middle school education--United States--Philosophy; Teaching--Philosophy
This study examined a hypothesized relationship among teacher beliefs, teacher behaviors, classroom climate, student engagement, and student outcomes. The researcher used teacher ( N = 6) and student ( N = 12) interviews, observations, and the...
US consumers spend $87 million annually on sporting goods and services (National Sporting Goods Association, 2008). Each year sporting goods manufacturers also spend millions of dollars creating innovative products for consumers looking to improve...
Evidence suggests that cortical minicolumns are reduced in size and increased in number in individuals with autism spectrum disorder (ASD), especially in the dorsolateral prefrontal cortex (DLPFC). More specifically minicolumns in individuals with...
Periodontitis--Treatment; Peptides--Therapeutic use
Periodontitis and its systemic sequelae remain a major public health problem and
developing a cost-efficient therapy will benefit healthcare worldwide. Adherence of
Porphyromonas gingivalis to Streptococcus gordonii facilitates colonization of the...
Ischemic heart disease is the leading cause of mortality and morbidity in Western societies. Thus, understanding the molecular mechanisms to reduce myocardial ischemia and limit infarction size are of great importance. Ample evidence has shown that...
Narrative causal understanding is related to a variety of school-related skills such as reading comprehension, and memory. Previous research shows a developmental trend in the ability to use and understand causal connections that begins at age 4...
Metaphor; English language--Rhetoric--Study and teaching
This dissertation is a theoretical examination and textual analysis of the metaphors used to describe the act of writing and the teaching of writing. Within Rhetoric and Composition, there are specific conceptual metaphors that are instrumental to...
Introduction: Osteoarthritis (OA) is a clinical condition affecting over 27 million Americans. There is no known cure for OA other than replacing the diseased joint with a joint prosthesis, total knee arthroplasty (TKA). Purpose: This study...
The term "promiscuity" is often used in academic literature and pejoratively
proliferated among society at large. The definition of promiscuity has not been clearly
and consistently defined within research and varies significantly from...
Chronic periodontitis is strongly associated with composition of the oral biofilm
occupying the gingival crevicular aspect of the tooth and its associated root. Some gram-negative,
"red complex" bacteria instigate periodontal bone loss in...
Aquatic ecosystems face major transformations as humans increasingly alter their environment by introducing exotic species and changing the temperature regime and nutrient availability of freshwater systems. The impacts of such alterations of...
Algebra--Study and teaching (Secondary); Motivation in education; Feedback (Psychology)
The double-blind study used two intact ninth grade high school Algebra One classes for a total sample size of 46. Within each of the classes the participants were assigned randomly to one of three treatment groups: self-referenced feedback,...
