c-Myc dysregulation is one of the most common abnormalities found in human cancer. MicroRNAs (miRNAs) are functionally intertwined with the c-Myc network as multiple miRNAs are regulated by c-Myc, while others directly suppress c-Myc expression. In...
Channel modification has played a vital part in shaping the rivers and streams as
they are seen today. Channel modifications range from the construction of dams and levees
for flood control purposes to channelization of an existing meandering...
Dimorphism is a highly conserved process in fungi in which a transition between a unicellular, yeast-like growth form and either a unicellular or multicellular, filamentous growth form occurs in response to several different environmental cues. The...
Computer sound processing; Computer-assisted instruction; Educational games
Educational games have steadily entered classrooms as a means of challenging advanced students and tutoring those lacking comprehension. However, without adequate educational benefits, instructors are struggling to continually justify the marginal...
In the retina, the receptive fields (RFs) of most neurons are comprised of an excitatory center and a suppressive surround. Retinal ganglion cell (RGC) RF center excitatory input arises from bipolar cell (BC) inputs, while their surround arises...
Inflammation is now recognized as an important factor in several age-related diseases such as arthritis, atherosclerosis, multiple sclerosis and diabetes. In each case, sub-clinical chronic inflammation occurs over years and leads to progressive...
Lead Zirconate Titanate (PZT), known for its ferroelectric properties, is widely used in micro-electromechanical (MEMS) and nano-electromechanical (NEMS) devices. PZT is a ceramic material that is most commonly found in its sol gel form, which...
Quorum sensing (Microbiology); Cellular signal transduction; Bacterial genetics
Quorum sensing in the oral pathogen Aggregatibacter actinomycetemcomitans is dependent upon the soluble signaling molecule AI-2, but it is not known how the initial detection of AI-2 is coupled to the downstream regulation of gene expression that...
Reperfusion of the ischemic lung causes pulmonary arteriolar vasoconstriction and reduces alveolar perfusion. Lung ischemia-reperfusion (IR) injury leads to platelet and leukocyte activation which could contribute to decreased alveolar perfusion...
Architecture; Buildings; Religious facilities; Interiors; Rooms & spaces; Cults; Sculpture; Portraits; Men; Emperors; Rulers; People associated with politics & government; Clothing & dress; Architectural elements; Walls; Pilasters;...
Shows "the end wall (frescoed) and the side wall (on the south side) with the reconstruction of the architectural order." (Caption, p. 145); "The Hall of the Colossus was deliberately set in the northeast corner of the Forum, at the...
Bioinformatics; Breast--Cancer--Treatment; Medical care--Data processing
Statistical models have been the first choice for comparative effectiveness in clinical research. Though effective, these models are limited when the data to be analyzed do not fit the assumed distributions; which is mostly the case when the study...
The distance education literature is lacking studies investigating the construct of social presence, the value placed on it by online learners, and whether its existence in text-based environments is necessary for learning, satisfaction, and...
The goals of this dissertation is to further the understanding of the roles of two genes identified by differential display polymerase chain reaction (ddPCR) of cat visual cortex as candidate genes to play a role in visual cortical plasticity....
Community college students--Transfer; Academic achievement; College attendance
The reverse transfer literature contains studies investigating the demographic characteristics of postsecondary students that attended a community college after attending a four-year institution, and their proportion in the community college...
The Y family of DNA polymerases in higher eukaryotes contains at least four members which are implicated in potentially error-prone replication through unrepaired damage in the genome. These proteins are encoded by the REV1, POLH, POLI, and POLK...
This dissertation is an exploratory study of teacher risk taking. The risk-taking literature in education and other types of organizations is lacking in studies exploring the concept of healthy risk taking and how that risk taking is related to...
Multicultural education--Indiana; Teachers--Training of
This study assessed the efficacy of diversity training in teacher education programs at two Indiana universities from the viewpoints of teacher educators and teacher education majors. Three research questions guided the study: (a) To what extent...
Unrepaired DNA damage poses a serious threat to the genetic stability of a replicating cell. One mechanism of tolerating this damage is translesion DNA synthesis (TLS), in which an accessory polymerase synthesizes DNA directly across from a damaged...
Wind power has the potential to provide access to electricity to areas lacking the resources to create industrial power plants, as well as supplement residential energy supplies. The low resource investment and ease of installation make it ideal...
