N-acetyltransferase 1 (NAT1) is a phase II metabolic enzyme responsible for the biotransformation of aromatic and heterocyclic amine carcinogens such as 4-aminobiphenyl (ASP). NAT1 catalyzes N-acetylation of arylamines as well as the 0-acetylation...
Dining room in Hillside House, home of Mr. and Mrs. Graddy Cary in Indian Hills, near Louisville, Kentucky. Wood paneled walls with two windows. Rectangular table with lowered sides and a doily and low bowl of tulips neatly on top. Five chairs line...
Recent advances in understanding the molecular mechanisms of mutagenesis indicate that most mutations are dependent on the activity of translesion synthesis DNA polymerases. The impact of reducing the level of these polymerases on mutagenesis and...
One of the most nationally-recognized, two-year legislative reform initiatives in the U.S. began in Kentucky with the passage of the Kentucky Postsecondary Education Improvement Act of 1997 (HB1). This exploratory, cross-sectional, correlational...
The role of the active site tyrosine residue in the Co-C5' bond activation in the
context of adenosylcobalamin-dependent mutases has been computationally
investigated. The density functional, complete active space self-consistent field
and quantum...
The goal of this longitudinal, multilevel study was to develop a better understanding of poor renter households' mobility patterns by identifying the relative importance of individual and contextual variables. Variability in neighborhood poverty...
Human exposure to mercury has been shown to cause a number of adverse health outcomes, predominantly neurological effects. The developing fetus is most susceptible, and even low levels of exposure have been shown to produce nervous system deficits....
Portrait of unidentified woman, with eyes lowered, wearing a cap with lace decoration and a dress with lace overlay and a large corsage. Location of photo studio: New York (N.Y.). Title supplied by cataloger.
Freight cars filled with iron ore. A man stands on top of one car guiding a bucket of ore. Beyond the trains are a barge and smaller ships in the water. Title: (75)-7965-Unloading iron ore from lake vessels - old and new methods - Cleveland, O....
Railroad stations; Railroads; Union Station (Chicago, Ill.); Buildings; Bridges
Overhead view of Union Station in Chicago and the Chicago River. Two buildings are in the background with rows of train platforms in front. To the left is the Chicago River with a boat and barges visible. In the foreground is a bridge crossing the...
This mosaic's "border consists of two rows of solids in perspective, each with a dot on its face, and between these a rich acanthus scroll. Except in the outer left row the solids meet in the middle. The acanthus branches spring from two...
Streets; Construction; Construction equipment; Sewerage; Bridges; Railroad tracks
Hiawatha Avenue and Louisville Avenue looking south. Wood bridge running next to a cluster of railroad tracks. A Street Closed sign is at the end of a lowered crossing gate.
Streets; Construction; Construction equipment; Sewerage; Men; Construction workers; African Americans
First Street between Ashland Avenue and Wentworth Avenue looking south. Four men, one of them African American, stand below ground in a large and deep trench or tunnel with wood beams running above. One man holds the end of a pipe being lowered...
Lillian and Elizabeth Fletcher stand with their backs to shelves full of bound books. They are wearing mid-calf length dresses and each is holding a book. Lillian appears to be reading while Elizabeth has lowered her book and is looking at the...