This thesis is divided into two parts below. Part I Adriamycin (ADR) can produce nephrotoxicity in rodents. The underlying mechanism may relate to ADR induced oxidative stress. In this study, we used transgenic mice (NMT3), which over-expressed the...
The fundamental question of the exact nature of the role played by TNF in the failing myocardium remains one of contention. Many preclinical studies have demonstrated beneficial effects with TNF antagonism and recently the dichotomous role played...
Microfabricated planar solar cells with an active solar collection area of 0.04cm2 were fabricated on n-type silicon wafers to test the viability of sputtered amorphous thin film photovoltaics for potential use in amorphous multijunction cells or...
This thesis chronicles my journey within the framework of a hero's journey, as a theatre artist in the Master of Fine Arts program at the University of Louisville's Theatre Arts Department. This thesis is divided into six chapters that explore the...
Rapid Electrokinetic Patterning (REP) is a relatively new method for collecting and manipulating micrometer-scale particles at an electrode surface. REP is an AC electrokinetic technique that uses induced fluid motion to capture and manipulate...
Periodontitis--Treatment; Peptides--Therapeutic use
Periodontitis and its systemic sequelae remain a major public health problem and
developing a cost-efficient therapy will benefit healthcare worldwide. Adherence of
Porphyromonas gingivalis to Streptococcus gordonii facilitates colonization of the...
Polychlorinated biphenyls (PCBs) are persistent environmental pollutants which
are detectable in the serum of all American adults. Amongst PCB congeners,
PCB 153 has the highest serum level. PCBs have been dose-dependently
associated with suspected...
Plague--History--Europe; Black Death--Social aspects--Europe; Erotica--Europe--History; Idols and images--Europe--History; Superstition--Europe--History
This thesis examines a large corpus of enigmatic pilgrimage badges dating from
roughly 1350-1500 CE. The badges were brought to light during archaeological
excavations of water sites throughout the Schelde Estuary in the Netherlands, the
riverbanks...
Acridine is a compound that has a ring system similar to anthracene except that one of the CH groups is replaced by a -N- group. It is possible for this compound to have desmotropic forms as those that follow. When an amino group is present in the...
Few previous studies have compared microbial communities in subterranean and surface environments. Chemical analyses used to characterize the surface and cave microbial environments indicated limited exchange between surface and subsurface waters....
Reperfusion of the ischemic lung causes pulmonary arteriolar vasoconstriction and reduces alveolar perfusion. Lung ischemia-reperfusion (IR) injury leads to platelet and leukocyte activation which could contribute to decreased alveolar perfusion...
The Technical Advisory Group (TAG) of the Innovative Treatment Remediation Demonstration Program (ITRD) made technology recommendations after reviewing thirty in situ remediation technologies for implementation at the Paducah Gaseous Diffusion...
The fundamental importance of a definite knowledge of the quantity of each amino acid yielded by the several food proteins justifies the expenditure of much effort in studying the analytical methods in order that these may be improved or their...
Slavery and the church--Kentucky--Louisville; Slavery--Kentucky--Louisville; Louisville (Ky.)--Church history
In the one hundred and forty years of Louisville's existence, it has grown from a log cabin settlement with no churches to a city with 269 churches and church property valued at over $30,000,000. It is impossible to measure the moral and religious...
Protective coatings; Microelectromechanical systems
PARYLENE (poly-para-xylylene) is mostly used as a conformal protective polymer pin-hole free coating material to uniformly protect any component configuration on diverse substrates. This thesis describes in detail how the unique properties of...
Discrimination in criminal justice administration--United States; Drug control--Social aspects--United States; War on Terrorism, 2001- --Social aspects; Crime and race--United States; United States--Race relations
This thesis is an examination of the relationship between race and ethnicity and the American justice system. It is a comparative case study of the racial dimensions of the War on Drugs in the domestic criminal justice system and the ethnic...
Liquid gallium (Ga) spontaneously alloys with thin films of metals such as Ag, Au, Pt Al, and Cu at near or even below room temperature resulting in rapid self-assembly of nanostructures. In this dissertation, studies of the formation of these...
Integrated circuits--Design and construction; Integrated circuits industry--Technological innovations
Lithographic processes for printing device structures on integrated circuits plays a major role in the semiconductor industry. This project aims at designing and fabricating a programmable mask for a direct write lithography system which can...
The importance of physical activity in preventing disease and promoting health is increasingly evident in health outcomes research. Although most adults in the U.S. have initiated exercise programs at some point in their lives, research suggests...
Polycyclic aromatic hydrocarbons; Fetus--Effect of tobacco on
Polycyclic aromatic hydrocarbons (PAH) are chemicals generated from the incomplete combustion of organic materials, including tobacco smoke. Some PAH are known to be mutagenic and carcinogenic in humans, and of concern for the fetus when women...
