Neurosphere forming cells (NSFCs) have been derived from cultures of adult olfactory neuroepithelium obtained from patients and cadavers in serum rich medium. These neural progenitors remain undifferentiated when maintained in serum rich medium but...
Recent studies indicate post-translational deacetylation by members of the superfamily of histone deacetylase complexes (HDACs) is necessary for oligodendrocyte precursor cell (OPC) differentiation into mature oligodendrocytes (OLs). However, it...
Spinal cord injury (SCI) can be divided into two distinct stages, an initial mechanical impact and a later "secondary injury" resulting from a cascade of cytokines triggering a spreading demyelination and apoptosis of neurons and glia...