The objective of my dissertation research was to determine the role of chemical signals in conveying information regarding an individual's health status and suitability as a mate in humans and to examine the role that commensal microflora play in...
Females have a higher incidence of autoimmune diseases than males for reasons that are currently unknown. CD4+CD25+ regulatory T cells play an important role in the maintenance of immunological homeostasis and self-tolerance by suppressing...
20S proteasome, essential component of protein degradation mechanism, is important to maintain homeostasis. Its malfunctions have been associated with several pathological conditions. This study presents an extensive study of murine cardiac 20S...
Art--Economic aspects--Nigeria; Anatsui, El, 1944-; Nigeria--Foreign economic relations
This paper is specifically concerned with contemporary artist El Anatsui, and his impact upon the region in which he lives and works in Nsukka, Nigeria. El Anatsui's large-scale wall sculptures—created by joining recycled aluminum distillery...
The fundamental question of the exact nature of the role played by TNF in the failing myocardium remains one of contention. Many preclinical studies have demonstrated beneficial effects with TNF antagonism and recently the dichotomous role played...
Hepatitis C virus--Research; Interferon--Therapeutic use; Adenosylmethionine
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease in the United States and is a huge burden on the US healthcare system. The FDA-approved traditional standard of care for HCV is pegylated interferon-alpha (lFNα) combined...
This dissertation deals with various imidazole compounds with emphasis on hydrogen bond interactions and weaker intermolecular forces. New amide functionalized polyimidazole metal binding pockets are able to form intramolecular six-membered...
Computer chess; Chess--Computer programs; Games and technology; Computer networks--Security measures
Cheating in chess can take many forms and has existed almost as long as the game itself. The advent of computers has introduced a new form of cheating into the game. Thanks to the computational power of modern-day computers, a player can use a...
Rhetoric--Study and teaching (Higher); Academic writing--Study and teaching--Social aspects
Scholars in rhetoric and composition have heralded a new way of thinking about writing, referring to the change as a paradigm shift (Hairston, Young) or naming the new direction a "social turn" in rhetoric and composition (Bizzell,...
The goals of this dissertation is to further the understanding of the roles of two genes identified by differential display polymerase chain reaction (ddPCR) of cat visual cortex as candidate genes to play a role in visual cortical plasticity....
Long-term exposure to harmful carcinogens like benzo[a]pyrene (BaP) are linked to lung cancer. Benzo[a]pyrene diol epoxide (BPDE), the ultimate carcinogen produced by BaP bioactivation, is believed to play an important role in lung carcinogenesis....
Colon (Anatomy)--Cancer--Genetic aspects; Cancer cells--Mathematical models
Research over the past twenty five years has led to the development of the hypothesis that colorectal cancer is caused by the accumulation of mutations in tumor suppressor genes and proto-oncogenes. The last ten years has also revealed that the...
Ischemic heart disease is the leading cause of mortality and morbidity in Western societies. Thus, understanding the molecular mechanisms to reduce myocardial ischemia and limit infarction size are of great importance. Ample evidence has shown that...
T lymphopoiesis has been an intense focus of immunological research since the discovery of the major histocompatibility complex (MHC) and T cell mediated transplant rejection. Additionally, researchers have long appreciated the role of T cells, and...
Neurosphere forming cells (NSFCs) have been derived from cultures of adult olfactory neuroepithelium obtained from patients and cadavers in serum rich medium. These neural progenitors remain undifferentiated when maintained in serum rich medium but...
Women refugees; Women immigrants; Women--Violence against; Stress management for women
An interest in privileging the voices of women who are marginalized in many parts of the world coupled with knowledge of the restorative properties of music cultivated this qualitative study. Seven women, ages 20-49 years of age, from three...
In the retina, the receptive fields (RFs) of most neurons are comprised of an excitatory center and a suppressive surround. Retinal ganglion cell (RGC) RF center excitatory input arises from bipolar cell (BC) inputs, while their surround arises...
Feminism in literature; Self-perception in literature; Women in literature; Chen, Ran, 1962-; Tan, Amy
With increasing cross-cultural infiltrations and accelerated interflows among people of all nationalities in this globalized world, the focus of comparative literature has experienced a shift from traditional Eurocentric cannons to a broader space...
The aim of this study was to determine if playing 5 soccer matches in 4 weeks after 8 weeks of strength, conditioning and soccer training further improves aerobic and anaerobic performances. Ten college soccer players (20.1 ± 1.2 yr) completed...
Nontraditional college students--Kentucky--Louisville; English language--Rhetoric--Study and teaching (Higher); College freshmen--Kentucky--Louisville
This dissertation explores the role first-year composition (FYC) courses play in the academic lives of working-class adult students in the University of Louisville, an institution that, during portions of its long history, has been a valuable...
