Address: 919 Cherokee Road, Louisville, Kentucky. A home is being sand-blasted to clean the brick. The machine to the right of the home creates the pressure to blast the sand. One man stands by the engine as another works with a tank. Pulleys are...
Air void structure in hardened concrete is critical to its durability. This project mainly focuses on investigating the air void system in hardened concrete with the microscopic analysis Linear Traverse Method specified by ASTM Specification...
Background The anthracycline doxorubicin (DOX) is widely used as an effective antineoplastic drug. Cardiotoxicity leading to congestive heart failure is the primary factor limiting the clinical use of DOX. However, although a variety of approaches...
Heart--Hypertrophy; Hydrogen sulfide--Therapeutic use
Background: Although matrix metalloproteinase (MMPs) and tissue inhibitor of metalloproteinase (TIMPs) play a vital role in tumor angiogenesis and TIMP-3 causes apoptosis, their role in cardiac angiogenesis is unknown. Interestingly, a disruption...
Background: Helicobacter pylori (Hp) establishes life-long gastric infection in billions of humans, and is often responsible for diseases such as peptic ulcer and gastric cancer. Cumulative actions of genetic drift and natural selection over...
Bi-stable buckled MEMS (micro-electromechanical systems) diaphragms have a myriad of uses in the MEMS field for their large out-of-plane deflections. Buckling is a phenomenon brought upon by a compressive stress. Diaphragms are large aspect ratio,...
Cardiology--Research--Methodology; Microfluidics--Equipment and supplies
Cardiovascular disease (CVD) is the leading cause of death in the United States and accounts for nearly 1,372,000 deaths each year. In addition, ~81 million Americans suffer from some form of CVD. Understanding the molecular basis of various...
Hypertension--Genetic aspects; Coronary heart disease--Genetic aspects; African Americans--Health and hygiene
Cardiovascular diseases, including hypertension, are the leading causes of death in
the United States. African-Americans carry the highest burden of disease with 32% of
adults with hypertension. Blood pressure (BP) dipping, defined as a drop of>...
Microelectromechanical systems; Pumping machinery; Drug infusion pumps
Dermal wounds, including bed sores, pressure ulcers, and diabetic ulcers have a large impact on American healthcare costing up to $7 billion per year. Adequate pharmaceutical remedies applied at constant rate could prove to increase the healing...
United States--Foreign relations--China; China--Foreign relations--United States; United States--Foreign relations--Taiwan; Taiwan--Foreign relations--United States; China--Foreign relations--Taiwan; Taiwan--Foreign relations--China
During the 2004 Presidential Election in the Republic of China, President Chen Shui-bian proposed two referenda. These referenda dealt with relations with the People's Republic of China. The People's Republic of China reacted very strongly against...
Equations of state attempt to describe the relationship between temperature (T), pressure (P), and molar volume (v) for a given substance or mixture of substances. The ideal gas law is the simplest form of an equation of state. An ideal gas can be...
Myocardial infarction; Glucose--Metabolism; Mitochondrial DNA
Heart failure is a leading cause of morbidity and mortality in the USA. During the development of heart failure, many cardiac parameters change at the same time including fuel metabolism, oxidative stress and mitochondrial function. Each of these...
Hematite synthesized by low pressure oxygen plasma has been shown previously to exhibit promising characteristics as a photo-anode for a photoelectrochemical water splitting cell. It is cheap, stable and has a 2.1 eV bandgap and exhibits a...
Hemolysis, the major cause for specimen rejection in clinical laboratories is defined as the rupture of red blood cell membranes, resulting in the release of hemoglobin into the plasma. Blood flow in needles causes hemolysis resulting in...
Educational tests and measurements--Kentucky; Educational accountability--Kentucky; School improvement programs--Kentucky
High-stakes accountability, standards for improvement, global perspectives, and social considerations are re-defining the educational process. These powerful forces shake foundations and traditions, restructure organizational expectations, and...
In this dissertation, standardized methods for measuring electron emission (EE) from nanostructured materials are established. Design of an emitter array platform, synthesis and nanomanipulation of different types of are successfully conducted....
Business logistics; Production management; Manufacturing processes; Industrial efficiency
In today's competitive business environment, companies face enormous pressure and must continuously search for ways to design new products, manufacture and distribute them in an efficient and effective fashion. After years of focusing on reduction...
INTRODUCTION: Heart failure is a major and growing public health concern. Although heart failure has been considered an inexorable and progressive disorder, emerging evidence suggests that some patients may have reversible left ventricular...
Mixed-effects model is an efficient tool for analyzing longitudinal data. The random effects in mixed-effects model can be used to capture the correlations among repeated measurements within a subject. The time points are not fixed and all...
Sleep apnea syndromes; Overweight persons--Health and hygiene; Obesity
Overweight and obesity is a major contributing factor in an estimated 70% of all obstructive sleep apnea (OSA) cases. Approximately five percent of the adult population has OSA, and the numbers continue to soar with the rising prevalence of...
