Most industrial countries face with some form of housing problems. As a result, each state has adopted a variety of housing policies. Policy methods of government authorities in meeting the housing gap and addressing the low income families'...
It has been estimated that 30% of all cancer deaths in the U.S. are associated with obesity. It is well-established that obesity promotes low-grade chronic inflammation, however the mechanisms by which obesity-induced chronic inflammation may...
Aquatic ecosystems face major transformations as humans increasingly alter their environment by introducing exotic species and changing the temperature regime and nutrient availability of freshwater systems. The impacts of such alterations of...
The purpose of this study was to determine the effects of acute glutamine supplementation on maximal performance and recovery from high-intensity exercise. In a placebo-controlled, crossover study, seven (six males and one female) healthy subjects...
This thesis is a personal examination of the process of creating, developing and portraying the character of Dionysus in University of Louisville's 1996 production of Euripides' The Bacchae. It begins with an examination of my acting process prior...
Acting; Shakespeare, William, 1564-1616--Characters--Queen Margaret; Shakespeare, William, 1564-1616. King Richard III
This thesis is a brief examination of what is required to create a successful performance onstage, where a successful performance is defined by the audiences understanding of the text through the actor's performance. With that understanding comes a...
Monoclonal antibodies directed toward tumor associated antigens are FDA approved anticancer reagents used commonly in the clinic. Administered antibodies initiate tumor cell death through several mechanisms. Improving immune mediated mechanisms,...
Inflammation is now recognized as an important factor in several age-related diseases such as arthritis, atherosclerosis, multiple sclerosis and diabetes. In each case, sub-clinical chronic inflammation occurs over years and leads to progressive...
Acting; Eno, Will, 1965---Characters--Man; Eno, Will, 1965- Flu season
This thesis examines my work on the role of Man in the University of Louisville's 2011 production of Will Eno's The Flu Season directed by James Tompkins. It is composed of three primary chapters: rehearsal process, character development, and...
The motivation to determine a viable alternative to petroleum based energy has risen in recent years due to increased greenhouse gas emissions, environmental pollution, and the fear of exhausting oil and natural gas reserves. Biodiesel derived from...
This thesis explores my work on the role of Charles Condomine in a production of Noel Coward's Blithe Spirit directed by James Tompkins. It is broken down into three main chapters covering the rehearsal process, character development, and...
The purpose of this dissertation was to demonstrate that a new method of direct intracellular energy delivery was effective in maintaining viability of in vitro Human Umbilical Vein Endothelial Cells (HUVECs) when exposed to chemical ischemia for...
Enzymatic hydrolysis is the most common method of producing fermentable sugars from lignocellulosic biomass. Limitations to this step include the high cost of enzymes, and the time required to process the biomass. To increase the throughput and...
This thesis chronicles my journey within the framework of a hero's journey, as a theatre artist in the Master of Fine Arts program at the University of Louisville's Theatre Arts Department. This thesis is divided into six chapters that explore the...
Wind energy provides an attractive power source as an alternative to fossil fuels because it is abundant, clean, and produces no harmful emissions. To extract more energy from the wind we need to increase the wind turbine size. However, the...
The immune system is of profound importance for host survival due to its ability to clear many acquired diseases. In case of infections and cancer, disease arises due to under-performance of immune system. Whereas in autoimmunity and...
Water treatment facilities strive to provide potable drinking water to the community which they service. The most common way of insuring drinkable water that is free of pathogens is water chlorination, but this can lead to the production of...
Cancer accounts for nearly one-quarter of deaths in the United States, exceeded only by heart diseases. Despite the development of various strategies to treat cancer, it remains one of the most deadly diseases worldwide due to the limited effects...
Gold nanoparticles (AuNPs) have attracted enormous attention in the field of nanotechnology for applications such as, immunoassay, drug delivery, contrast enhancement and tumor therapy. The typical range of gold nanoparticles varies from 1– 150...
Human adenoviruses (Ads) can infect and replicate in cells at different cell-cycle stages. Ads with the E1 B55K deletion preferentially replicate in cancer cells and cause oncolysis. Our laboratory has previously shown that the Ad E1 b gene is...
