"The vast majority of prehistoric sculptures depict either animals or humans. In the earliest art, humankind consists almost exclusively of women as opposed to men, and painters and sculptors almost invariably showed them nude […]. When...
"This is the painting Dali took to show Freud in London. It belonged formerly to Edward James." (Caption); "At Zürs […] Dali embarked on a new experiment: the composition, in French, of a 'paranoaic' poem, The Myth of Narcissus,...
A common research interest in medical, biological, and engineering research is determining whether certain independent variables are correlated with the survival or failure times. Standard statistical techniques cannot usually be applied for...
Environmental education; Couples; Population control;
A man and woman look at information on a table that advocates a two-child only policy as a means of population control. A group of people can be seen sitting on the ground behind them. A poster on the table says, "The two child family means...
Medical care--Decision making; Decision making--Simulation methods
A variety of methodologies have been employed for decision making related to the treatment of diseases/injury. Decision trees are a functional way in which to examine problems under uncertainty by providing a method to analyze decisions under risk...
Background The anthracycline doxorubicin (DOX) is widely used as an effective antineoplastic drug. Cardiotoxicity leading to congestive heart failure is the primary factor limiting the clinical use of DOX. However, although a variety of approaches...
Background: CHF is a chronic disease that affects nearly five million people each year; in which at least 500,000 are newly diagnosed cases. Patients diagnosed with this disease will be under a physician's care for the remainder of their life. It...
Cancer accounts for nearly one-quarter of deaths in the United States, exceeded only by heart diseases. Despite the development of various strategies to treat cancer, it remains one of the most deadly diseases worldwide due to the limited effects...
Complement, an early recognition system of innate immunity that senses local tissue damage and infection, cross-talks with and regulates other signaling systems, including Toll-like receptor (TLR) pathways. In the context of periodontitis,...
Jamestown Settlement--History; Great Britain--Colonies--America--History--17th century; Leadership--History; Virginia--History--Colonial period, ca. 1600-1775
English experience gained from colonization attempts in the New World and in Ireland, as well as military expeditions to the European continent and the New World, helped make Jamestown more successful than any previous English colonial venture in...
Sculpture; Signs (Notices); Advertisements; Advertising; Electric signs; Electron tubes; Communication; Communication devices; Language; Slogans; Cities & towns; Night; Night photographs; Architecture; Buildings; Walls; Streets; Roads;...
Excerpt from the Survival series. "Jenny Holzer extended the use of language in art to another dimension by presenting words alone; for the viewer, looking and reading became one and the same act. […] In graduate school at the Rhode Island...
Genes in folate metabolizing pathway are responsible for modulating key enzymes in folate metabolisms necessary for DNA synthesis and repair and influence DNA methylation. Irregularity in DNA methylation may modify tumor phenotype response to...
Heart failure is the most frequent cause of mortality in western countries. Currently, there is no cure treatment for heart failure and the long term survival rate following heart failure is poor, with one third of patients dying within a year of...
Human adult olfactory epithelium contains neural progenitors (hONPs) which replace damaged cellular components throughout life. Methods to isolate and expand the hONPs have been developed in our laboratory. In response to morphogens, the hONPs...
Human arylamine N-acetyltransferase (NAT) is a phase II cytosolic enzyme that occurs as two isozymes, NAT1 and NAT2. This family of polymorphic enzymes catalyzes the detoxification and/or activation of many aromatic and heterocyclic amine drugs and...
Hypoxia is characterized by an inadequate oxygen supply to the tissues in
proportion to their metabolic needs, and is a primary factor in traumatic CNS
injury, strokes, cardiopulmonary diseases, and obstructive sleep apnea. The
cAMP-dependent...
In recent years, a number of computational and statistical problems for identifying SNP-SNP interactions in high dimensional survival data have been studied, and several data mining approaches have been proposed. However, the relative performance...
In the United States substance abuse takes a toll that is costly in both economic and human terms. In 2005 we paid 467.7 billion dollars to address the consequences of substance abuse, and each year we have lost an estimated 537,000 of our fellows...
In this dissertation research, we aim to solve problems of two types of survival data, clustered survival data with potentially informative cluster size and sojourn time data. The methods for these two types of data are different. However, both...
Integrins are major receptors for cell adhesion to the extracellular matrix, and play key roles in various cellular processes including adhesion, migration, proliferation and survival. Apart from developmental and physiological events, integrins...
