20S proteasome, essential component of protein degradation mechanism, is important to maintain homeostasis. Its malfunctions have been associated with several pathological conditions. This study presents an extensive study of murine cardiac 20S...
A blinded observational cross-sectional in vitro study was conducted to compare the diagnostic accuracy of observers viewing images made using cone beam computerized tomography (CBCT), panoramic radiography and linear tomography. The sample...
Coronary heart disease--Treatment--Cost effectiveness; Angioplasty; Medical laws and legislation--Kentucky
A myocardial infarction (MI) occurs when blood supply to the heart is cut off by a blockage in one of the coronary arteries. Most hospitals treat a patient with thrombolysis or a percutaneous coronary intervention (PC I). The latter has been...
Emergency medicine--Diagnosis; Emergency medical services
A retrospective study involving the secondary analysis of public health surveillance records was undertaken to characterize the reliability and validity of an EMS dispatch data-based scheme for assigning emergency patients to surveillance syndromes...
Fatigue--Diagnosis; Reaction time--Testing; Physical fitness for women; Women athletes--Physiology
Accumulated fatigue experienced during the competitive season can be detrimental to
athletic success. The purpose of the study was to identify a performance test that best correlated
with markers of fatigue in an attempt to detect accumulated...
Alcoholic liver disease (ALD) is a serious concern for the world's population. It is one of the leading causes of death and is also a huge economic burden. The biochemical mechanisms responsible for ALD are incompletely understood, therefore there...
Alcoholic liver disease (ALD) ranks among the major causes of morbidity and mortality in the world and effects millions of patients each year. Progression of ALD is well characterized and is actually a spectrum of liver diseases, which progresses...
Although not a criteria for diagnosis of autism, feeding difficulties are commonly found in this population. The purpose of this thesis is to provide further insight in the area of autism and feeding. Parents of children with and without autism...
Women refugees; Women immigrants; Women--Violence against; Stress management for women
An interest in privileging the voices of women who are marginalized in many parts of the world coupled with knowledge of the restorative properties of music cultivated this qualitative study. Seven women, ages 20-49 years of age, from three...
Liver--Diseases--Genetic aspects; Liver--Effect of arsenic on; Arsenic--Toxicology
Arsenic exposure in drinking-water is a significant worldwide health problem. It causes adverse human health effects, such as cancer, increases the risks for others such as cardiovascular disease, and accelerates atherosclerosis. In this study, we...
Attachment Disorder (AD) in children has been characterized by particularly alarming behaviors, yet the identification of this disorder for clinicians in community mental health agencies is problematic. The only available diagnosis that addresses...
Autism Spectrum Disorder (ASD) is an idiopathic pervasive neurodevelopmental disorder associated with various neuropathologies and immunological dysfunctions. Cytokines are regulatory proteins that facilitate communication between the immune and...
Background . Heart failure treatment guidelines emphasize the importance of daily weight monitoring. To support this practice, the Health Care Financing Administration Heart Failure Demonstration Project (2000) was designed to evaluate the effect...
Background. Progression of alcoholic liver disease (ALD) is associated with an increase in fibrin extracellular matrix (ECM) and inflammation. Previous studies have shown that this accumulation of fibrin in ALD is mediated by impaired fibrinolysis....
Heart--Hypertrophy; Hydrogen sulfide--Therapeutic use
Background: Although matrix metalloproteinase (MMPs) and tissue inhibitor of metalloproteinase (TIMPs) play a vital role in tumor angiogenesis and TIMP-3 causes apoptosis, their role in cardiac angiogenesis is unknown. Interestingly, a disruption...
BACKGROUND: Regulated secretion of protein by salivary and other exocrine glands requires correct trafficking of soluble cargo proteins into secretory vesicles. However, the molecular mechanism of sorting in the parotid salivary gland is unknown....
Background: When rat salivary gland cells are cultured in vitro, they dedifferentiate within 24 h. Hypothesis: Growth factors will prevent de-differentiation of primary cultures of parotid gland cells, and they will induce differentiation of ParC5...
Because of limitations in randomized controlled trials, medical researchers are often forced to rely upon studies of observational data. Confounding is a major difficulty encountered in such studies that can create considerable bias in estimates of...
c-Myc dysregulation is one of the most common abnormalities found in human cancer. MicroRNAs (miRNAs) are functionally intertwined with the c-Myc network as multiple miRNAs are regulated by c-Myc, while others directly suppress c-Myc expression. In...
Student affairs administrators--Attitudes; College students--Mental health services
Calls for universities to better serve college students with mental illness have been growing. While a considerable literature base supports Corrigan's (2004) Social Cognitive Model of Mental Illness Stigma and the complex relationship among...
