Twitter; Museum visitors--Services for--Technological innovations; Museums--Technological innovations; Online social networks; Museums--Marketing
With the evolution of social networks and technological innovations, services such as Twitter provide a platform for increased dialogue and participation. Micro-blogging features enable individuals and organizations to communicate directly,...
Periodontitis--Age factors; Natural immunity; Age factors in disease
Age-related alterations in innate immunity are poorly understood. The identification of those mechanisms, which are dysfunctional in old age, will shed light on potential therapeutic strategies for chronic inflammatory diseases prevalent in the...
Exocytosis of intracellular granules is critical for conversion of inactive, circulating neutrophils to fully activated cells. The p38 MAPK pathway plays a central role in neutrophil exocytosis, although its mechanism of action is unknown. We used...
The vast knowledge of nucleic acids is evolving and it is now known that DNA can adopt highly complex, heterogeneous structures. Among the most intriguing are the G-quadruplex structures, which are thought to play a pivotal role in cancer...
A significant amount of effort has been put in developing tools to interpret Ground Penetrating Radar signals obtained during surveys. Currently, skilled and experienced users do most of GPR image interpretation. They use experience in deciphering...
MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level by repressing translation or stimulating mRNA degradation. In this study, I tested the hypothesis that miRNAs are differentially expressed in antiestrogen-sensitive MCF-7...
Acrolein--Toxicology; Stem cells--Effect of pollution on
Acrolein is a common pollutant present in ambient air, automobile exhaust, and tobacco smoke. Previous studies show that exposure to acrolein increases cardiovascular disease risk. To determine whether acrolein affect cardiovascular regeneration,...
Radio frequency allocation--Mathematics; Wireless communication systems--Mathematical models; Frequency spectra--Mathematical models
Multidimensional frequency estimation is a classic signal processing problem that has versatile applications in sensor array processing and wireless communications. Eigenvalue-based two-dimensional (2-D) and N -dimensional ( N -D) frequency...
Heart failure is the most frequent cause of mortality in western countries. Currently, there is no cure treatment for heart failure and the long term survival rate following heart failure is poor, with one third of patients dying within a year of...
Cancer accounts for nearly one-quarter of deaths in the United States, exceeded only by heart diseases. Despite the development of various strategies to treat cancer, it remains one of the most deadly diseases worldwide due to the limited effects...
Representing the complex data in a concise and accurate way is a special stage in data mining methodology. Redundant and noisy data affects generalization power of any classification algorithm, undermines the results of any clustering algorithm and...
Fontaine Ferry Park (Louisville, Ky.); Amusement parks; Shooting galleries; Carnival games
A mat is spread on the floor in front of the shooting gallery at Fontaine Ferry Park. The front of the counter reads, "5 shots 10." Behind the counter are a number of targets including circles on the back wall and a line of automated...
Our research activities are based on the catalytic systems that provide resource-saving synthetic methodologies through gold-catalyzed reactions of alkynes and alkenes. We have worked on three applications: i) an effective and straightforward...
Embryonic development requires the orchestration of temporally precise genetic events that culminate in the formation of a complete organism. The molecular mechanisms responsible for ontogenesis are regulated by environmental and somatic factors in...
Accelerated life testing; Reliability (Engineering); Service life (Engineering)
This dissertation is focused on finding lower confidence limits for the reliability of systems consisting of Wei bull components when the reliability demonstration testing (RDT) is conducted with zero failures. The usual methods for the parameter...
The inherited bone marrow failure syndromes (IBMFS) encompass a heterogeneous collection of rare disorders characterized by hematological abnormalities, generalized growth delays, and an increased incidence of malignant transformation. These...
The pulvinar is the largest nucleus of the human dorsal thalamus and is affected in a variety of brain disorders, such as schizophrenia. The experiments described in this dissertation elucidate key features of tecto-pulvino-cortical pathways as a...
Teachers of children with disabilities--Attitudes; Teacher-student relationships; Developmentally disabled children--Education; Affective education
The First Step to Success early intervention program (Walker, 1998) is a
secondary prevention intervention that targets primary grade children with moderate or
emerging behavior disorders. While the effectiveness of the First Step to Success...
The current status of our knowledge of synaptic plasticity comes largely from studies of the hippocampus and the context of learning and memory. We remain largely ignorant of plasticity in other neural systems and contexts. The molecular basis of...
When observers view a naturalistic (l/f) broadband image, the various spatial components present in the image stimulate many detecting-mechanisms that suppress each other. This suppression is anisotropic, being relatively greater for mechanisms...
